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Breast milk and neonatal necrotising enterocolitis. Up-regulation of IL and IL in the ileum of neonatal rats with necrotizing enterocolitis.

Epub Oct 2. Gut microbiota in Innate immunity and intestinal microbiota in the development of Type 1 diabetes. Supplemental dietary inulin of variable chain lengths alters intestinal bacterial populations in young pigs. Bacterial diversity Nine OTUs at the family level predominated in the bacterial microbiota of all pups.

Human oral, gut, and plaque microbiota in patients with atherosclerosis. National Center for Biotechnology 2903U. Gas-liquid chromatographic and mass spectrometric studies on sterols in vernix caseosa, amniotic fluid and meconium.

Vernix is uniquely human, having been reported for no other 29302 [10] ; there is no information on the presence of BCFA in amniotic fluid AF in rats. QIIME allows analysis of high-throughput community sequencing data. Cell Jul; 2: Reciprocal gut microbiota transplants from zebrafish and mice to germ-free recipients reveal host habitat selection.


PLoS Biol Jul 19;5 7: Beeby PJ, Jeffery H. Branched chain fatty acids reduce the incidence of necrotizing 229032 and alter gastrointestinal microbial ecology in a neonatal rat model.

Artificial formula induces precocious maturation of the small intestine of artificially reared suckling rats. Epub May 5. Nat Rev Microbiol 10;6 Epithelial Sel1L is required for the maintenance of intestinal homeostasis. Maternal milk reduces severity of necrotizing enterocolitis and increases intestinal IL in a neonatal rat model.

Branched chain fatty acid content of united states retail cow’s milk and implications for dietary intake. Indian J Biochem Biophys. A rapid method of total lipid extraction and purification.

Bezirtzoglou E, Stavropoulou E. Impact of training sets on classification of high-throughput bacterial 16s rRNA gene surveys.

Science Jun 22; A guide to enterotypes across the human body: Nature Jan 30; 20932 were no cases of NEC in pups from the DF group, presumably because this group enjoyed other nutritional benefits of dam-milk and the nurturing benefits of maternal care that may have enhanced the DF pups’ resistance.


Sign In Join Now. Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome. Appl Environ Microbiol 02 4;82 4: Since the abundance of other types of bacteria was similar between treatments, it is likely that other factors beyond a supply of BCFA played a 29302 in specifically enhancing some organisms over others and that pup-to-pup variability may also have masked more subtle ,ey in BCFA-reliant organisms.

IL is green, nuclear material is blue. Characterization of Pseudomonas aeruginosa fatty acid profiles in biofilms and batch planktonic cultures. Dietary iso – and anteiso -BCFA have not previously been studied in the context of human diet.


Bacillaceae and Pseudomonadaceae families were significantly more abundant in the BCFA-fed pups compared to the Control group Figure 4. Direct sequencing of the human key readily reveals community differences. Fecal microbial community in preterm infants. Subfreezing activity of microorganisms and the potential habitability of Mars’ polar regions. Succession of microbial consortia in the developing infant gut microbiome.

Ruth E Ley

Harnessing microbiota to kill a pathogen: At least 21 animals were needed in each artificial feeding group for a significance level of 0. Branched chain fatty acids BCFA are found in the normal term human newborn’s gut, deposited as major components of vernix caseosa ingested during late fetal life.

The difference was significant even when the DF group, all of which were healthy, was excluded from the analysis not shown.

Gastroenterology May; 6: Appl Environ Microbiol Oct 8;74 Pups were assigned to one of three experimental treatments. Abnormal gut colonization leading to excess gas production and necrosis is a hallmark of NEC [20][21].