PDF | On Apr 1, , SANTIAGO MUZZO PONS and others published Enfermedad de hand Schuller Christian. Purpose/Material and Method: To describe the clinical case of a month-old boy with Hand-Schuller-Christian disease. Exophthalmos was the only systemic. Diabetes insipidus and growth retardation are common manifestations of hypothalamic involvement in patients with Hand-Schuller-Christian disease ( HSCD).

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Hand-Schüller-Christian disease | Radiology Reference Article |

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Hand-Schuller-Christian Syndrome

Langerhans-cell granulomatosis can involve a single organ, or can be a systemic disorder. Langerhans cell histiocytosis may also affect the pituitary gland which makes hormones that control other glands and many body functions, especially growth.

Langerhans cell histiocytosis is most common in children and young adults. Definition NCI A neoplastic proliferation of Langerhans cells which contain Birbeck granules by ultrastructural examination. Three major overlapping syndromes are recognized: The clinical course is generally related to the number of organs affected at presentation.

There is involvement of multiple sites in one organ system, most frequently the bone. Patients are usually young children presenting with multiple destructive bone lesions.

Definition CSP enfeermedad of disorders of histiocyte proliferation which includes Letterer-Siwe disease; Hand-Schueller-Christian syndrome; and eosinophilic granuloma; Langerhans cells are components of the lesions.

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Related Topics in Histiocytosis. Hematology and Oncology Chapters. Hematology and Oncology – Histiocytosis Pages.

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hannd A group of rare disorders in which too many Langerhans cells a type of white blood cell grow in certain tissues and organs including the bones, skin, and lungs, and damage them. A neoplastic proliferation of Langerhans cells which contain Birbeck granules by ultrastructural examination.

A multifocal, unisystem form of Langerhans-cell histiocytosis.