Adenomatoid Odontogenic Tumour of the Maxilla – A Case Report with Review. 1 Reader. Dept of Oral Medicine and Radiology. SRM Dental College. Adenomatoid odontogenic tumour is a benign (hamartomatous), noninvasive lesion with slow but progressive growth. The 3 variants — follicular, extrafollicular . Adenomatoid odontogenic tumor is a hamartomous benign neoplasia of odontogenic origin. It appears mostly in young patients and females, the maxillary.

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The radiographic findings of AOT frequently resemble other odontogenic lesions such as dentigerous cysts, calcifying odontogenic cysts, calcifying odontogenic tumors, globule-maxillary cysts, ameloblastomas, odontogenic keratocysts and periapical disease [ 10 ].

Journal List Head Face Med v. The osontogenic course and follow-up were uneventful. Immunhistochemical localization of amelogenin in human adenomwtoid tumors, using a polyclonal antibody against bovine amelogenin.

Clinical features generally focus on complaints regarding a missing tooth. Birth of a term. Rings of columnar cells give rise to duct-like appearance Fig. Peripheral adenomatoid odontogenic tumor: Recurrence of AOT is exceptionally rare.

Both patients have been treated under general anesthesia for the removal of the lesions with unerupted tooth.

Adenomatoid odontogenic tumor of the mandible: review of the literature and report of a rare case

Immunohistochemical demonstration of bone morphogenic protein in odontogenic tumors. Comparing diagnostic arruracy between intraoral periapical and panoramic radiographs Dare et al.

J Oral Pathol Med. Indian J Dent Res. Finally, Gao et al. Clinical features Clinical features generally focus on complaints regarding a missing tooth.

The tooth 43 is located on the floor of this process. The peripheral lesions may show some erosions of the adjacent cortical bone [ 11 ].


Authors have analyzed the last 30 years of international literature and present hereby two cases of a rare neoplasm of the maxillary bones: WHO histological typing of odontogenic tumours. Odonotgenic AOT was predominantly found in the upper jaw maxilla: The adenomatoid odontogenic tumour: Racial pigmentation probably plays an important role in such cases [ 1617 tumir. Treatment is conservative and the prognosis is excellent. After the operation, the specimen was fixed in 4 per cent formal saline and prepared for histological examination.

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There was no evidence of recurrence and no apical resorption of the adjacent teeth could be observed Fig. Repair of an intrabony defect from an adenomatoid odontogenic tumor. The tumor is most often diagnosed in the second decade of life and women are about twice as many affected than men. However, the rare peripheral variant occurs primarily in the gingival tissue of tooth-bearing areas [ 9 ].

Panoramic radiograph six months after therapy. A case of multiple AOT-like jawbone lesions in a young patient-a new odontogenic entity? From the early s onwards 65 single cases of AOT excluding case series of more than 10 cases have been published.

Positive reactions for amelogenin in limited areas in AOT are also reported as well as in ameloblasts and in the immature enamel matrix [ 20 ]. AOT should be considered in the differential diagnosis of radiolucent jaws swelling, although its low incidence. Case report A year-old man was referred by his odotnogenic dental practitioner.

However, a variety of terms have been used to describe this tumor. Separating the lesion from mandibular bone caused no problems. Br J Oral Maxillofac Surg. Published online Aug Treatment and prognosis Conservative surgical enucleation is the treatment modality of choice. It is predominantly found in young female patients and usually located in the maxilla associated with an unerupted permanent tooth.


Immunohistochemically AOT is tu,or by positive reactions with certain cytokeratins. The tumor may be partly cystic, and in some cases the solid lesion may be present only as masses in the wall of a large cyst [ 14 ]. However, all of these tumog lesions did not show macroscopically visible pigmentation. Nodular aggregates of cells. The postoperative course was uneventful. Competing interests All authors disclaim any financial or non-financial interests or commercial associations that might pose or create a conflict of interest with information presented in this manuscript.

Adenomatoid odontogenic tumor of the mandible: review of the literature and report of a rare case

The AOT is over two times more located in the maxilla than in the mandible and the anterior jaw is much more affected than the posterior area.

Unerupted permanent canine are the theeth most often involved in AOTs. Pigmented lateral periodontal cyst and other pigmented odontogenic lesions. Many different names like adenoameloblastoma, odkntogenic adenomatoid tumor, adamantinoma, epithelioma adamantinum or teratomatous odontoma have been used before to define the lesion currently called AOT.

Whereas cementifying fibromas, dentinomas and compound odontomas demonstrated a positive reaction, all AOT as well as ameloblastomas and calcifying epithelial odontogenic tumors were negative.

Adenomatoid odontogenic tumor AOT is a relatively uncommon distinct odontogenic neoplasm that was first described by Steensland in [ 1 ]. In Philipsen and Reichart [ 3 ] presented a review based on reports published until which showed some interesting aspects regarding epidemiological figures of this tumor.