and pharmacological properties of Kigelia africana (Lam.) Balmkheera, Isopinnatal, Kigelin, Chemical constituents, Medicinal properties. Objective: Kigelia africana, a tropical tree, which has long been used in African . Analytical grade solvents (Fischer chemicals) were used for isolation and. cancer with drugs (pharmacotherapy) or with chemical compounds ( chemotherapy) in family comprises 21 species, of which Kigelia africana. (Lam. ) Benth is.

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The spectrum was carefully compare to phytol 1 H NMR spectrum with the main difference in the presence of extra allylic proton shift at 5. The combined fractions 10 to 13 was chromatographed on a preparative silica gel TLC plates eluted with a 5: Lapachol and derivatives as constituents of plant extracts are well documented for anti-inflammatory, antimicrobial, and antineoplasic activities Miranda et al.

Folk Medicines kigeliia Kurukshetra district Haryana. Ethnobotany and recent scientific kjgelia. Received Oct 24; Accepted Nov Alkaloid was conscupiously absent in the root of the study plant.

Chemical composition and antioxidant potentials of Kigelia pinnata root oil and extracts

Antioxidant activity measured in different solvent fractions obtained from Mentha spicata Linn.: The leaves of Kigelia pinnata were extracted successively with hexane and ethylacetate at room temperature and the extracts fractionated on an open silica gel column using hexane, ethylacetate and methanol gradient of increasing polarity.

It is also reported for its antioxidant activities Wenceslau et al. Spectrum Books Ltd; Important heteronuclear multiple-bond correlations of compound kigelis Click here to view. Kigelia africana, a tropical tree, which has long been used in African traditional medicine. Open in a separate window.

Higher absorbance of the reaction mixture indicates higher reductive potential.

New Constituents of Kigelia pinnata Leaves – SciAlert Responsive Version

Virgili F, Scaccini C. The structures of phenolic compounds which exhibited antioxidant activity in the ethyl acetate chemivals would need to be elucidated. A procedure to measure the antiradical efficiency of polyphenols.


The aqueous and methanol extracts of T. Though the plant is highly regarded for its unique medicinal potencies due to the presence of lapachol, squalene, naphthoquinones etc, the content of elaidic acid content in the oil calls for caution in the use of the plant in traditional medical therapy. National Center for Biotechnology InformationU.

Tannins are chemicald known to be useful in the treatment of inflamed or ulcerated tissues and have remarkable activity in cancer prevention Ruch et al. Amazingly, the three proton chemical shifts appeared as singlet each apparently due to the fact that each proton has no immediate neighbor for coupling. It was established that they caused lack of essential fatty acids Kummerow et al.

Simultaneously hermaphroditic shrimp use lipophilic cuticular hydrocarbons as contact sex pheromones. Alkaloids have been associated with medicinal uses for centuries and one of their common biological properties is their cytotoxicity Nobori et al. Niger J Health Biomedical Sci. Oxidative stress and neurodegeneration: Essential oil analysis and antimicrobial activity of eight Stachys species from Greece.

From the result presented in Table 1the entire composition of the oil fraction indicated compounds falling into different classes. Inhibition of activator protein-1, nf-k b, and mapks and induction of phase 2 detoxifying enzyme activity by chlorogenic chemocals. Fractions 5 to 8 yielded a golden yellow oil, trans-phytol IV while fraction 9 afforded a bright yellow oil 9Z,12Z -methyl octadeca-9,dienoate V.

Dietary trans fatty acids affect docosahexaenoic acid concentration in plasma and liver but not brain of pregnant and fetal rats.

The ethyl acetate residue was also eluted in a silica gel CC as for the hexane residue. In view of the various reports on the toxicity of elaidic acid, the therapeutic effect of the plant should be weighed along side its toxicity when administered in folk medicine. Special attention may have to be paid to the extraction kigella. The ethyl acetate-extract was decanted, filtered using a Whatman No.

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UV and IR spectroscopic techniques were used to carry out partial characterization of the oil and extracts.

J Clin Microbiol ; The Bignoniaceae family is noted for the occurrence of iridoids, naphthoquinones, flavonoids, terpenes, tannins, steroids, coumarins, saponins and caffeic acid in the fruits, stem, leaves and roots Akunyili and Houghton, [ 2 ]; Houghton et al.

University of Natal Press; An analysis by ABTS decolorization assay. This is an Open Access article distributed under the following Assignment of Rights http: Hexane, petroleum spirit, dichloromethane, ethyl acetate, methanol and ethanol used were analytical, while silica gel F and vanillin spray reagent were obtained from the chemical store of the Department of Chemistry, University of Ilorin, Nigeria.

Species that contain lapachol and several biogenetically related naphthoquinones e. None, Conflict of Interest: Isolation and structure of two new dihydroisocoumarins from Kigelia pinnata. Aqueous extract of the bark of Kigelia africana reverses early testicular damage induced by methanol extract of Carica papaya. The mixture was centrifuged at g for 10 min to collect the upper layer of the solution 2. Shell Oil Botswana; A new iridoid glycoside from Catalpa speciosa.

Novel lapachol derivatives and their antioxidant activity. Fractionation scheme for K.

Chemical composition and antioxidant potentials of Kigelia pinnata root oil and extracts

Solvents were re-distilled before use. Thus, the presence of these constituents in Kigelia pinnata partly supports the common traditional use of plant in the treatment of cancer. The pulverized plant material weighing g was extracted exhaustively with n-hexane at room temperature for five days.